Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Common genotypic polymorphisms in glutathione S-transferases in mild and severe falciparum malaria in Tanzanian children.

The American journal of tropical medicine and hygiene - 1 Aug 2009

Kavishe Reginald A, Bousema Teun, Shekalaghe Seif A, Sauerwein Robert W, Mosha Frank W, van der Ven Andre J A M, Russel Frans G M, Koenderink Jan B

Abstract excerpt

Malaria infection induces oxidative stress in the host cells. Antioxidant enzymes such as glutathione S-transferases (GSTs) are responsible for fighting reactive oxygen species and reduction of oxidative stress. Common GST polymorphisms have been associated with susceptibility to different diseas...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Child
Share to Child, Preschool
Share to Gene Expression Regulation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Predisposition to Disease

Share to Glutathione Transferase

Share to Malaria, Falciparum

Share to Polymorphism, Genetic

Share to Tanzania

Source

Identifiers

PMID: 19635899

Genes

GSTM1
GSTP1
GSTT1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19635899-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Common genotypic polymorphisms in glutathione S-transferases in mild and severe falciparum malaria in Tanzanian children.PMID 19635899Read ↗

Short report: Severe Plasmodium falciparum malaria in Cameroon: associated with the glutathione S-transferase M1 null genotype.Semantic proximity Read ↗

Host genetic variations in glutathione-S-transferases, superoxide dismutases and catalase genes influence susceptibility to malaria infection in an Indian population.Semantic proximity Read ↗

Polymorphism in glutathione S-transferase P1 is associated with susceptibility to Plasmodium vivax malaria compared to P. falciparum and upregulates the GST level during malarial infection.Semantic proximity Read ↗

Glutathione S-transferase gene polymorphisms (GSTM1, GSTT1, and GSTP1) in Egyptian pediatric patients with sickle cell disease.Semantic proximity Read ↗

Relation between glutathione S-transferase genes (GSTM1, GSTT1, and GSTP1) polymorphisms and clinical manifestations of sickle cell disease in Egyptian patients.Semantic proximity Read ↗

The role of red blood cell polymorphisms in resistance and susceptibility to malaria.Semantic proximity Read ↗

Association between the genetic polymorphisms of glutathione S-transferase (GSTM1 and GSTT1) and the clinical manifestations in sickle cell anemia.Semantic proximity Read ↗

Genetic polymorphism of cytochrome P450 1A1 (Cyp1A1) and glutathione transferases (M1, T1 and P1) among Africans.Semantic proximity Read ↗

CD36 T188G gene polymorphism and severe falciparum malaria in India.Semantic proximity Read ↗

Human genetic polymorphisms and asymptomatic Plasmodium falciparum malaria in Gabonese schoolchildren.Semantic proximity Read ↗

Analyses of Genetic Variations of Glutathione S-Transferase Mu1 and Theta1 Genes in Bangladeshi Tannery Workers and Healthy Controls.Semantic proximity Read ↗

Glutathione S-transferase polymorphisms may be associated with risk of oedematous severe childhood malnutrition.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.