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Article

The Host Genetic Diversity in Malaria Infection

1 Jan 2012

Abstract excerpt

Populations exposed to Plasmodium infection develop genetic mechanisms of protection against severe disease. The clinical manifestation of malaria results primarily from the lysis of infected erythrocytes and subsequent immune and inflammatory responses. Herein, we review the genetic alterations associated with erythrocytes or mediators of the immune system, which might influence malaria outcome. Moreover,...

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Identifiers

PMID: 23316245
DOI: 10.1155/2012/940616

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