Article
Candidate malaria susceptibility/protective SNPs in hospital and population-based studies: the effect of sub-structuring.
Malaria journal - 8 May 2010
Eid Nahid A, Hussein Aymen A, Elzein Abier M, Mohamed Hiba S, Rockett Kirk A, Kwiatkowski Dominic P, Ibrahim Muntaser E
Abstract excerpt
BACKGROUND: Populations of East Africa including Sudan, exhibit some of the highest indices of genetic diversity in the continent and worldwide. The current study aims to address the possible impact of population structure and population stratification on the outcome of case-control association-analysis of malaria candidate-genes in different Sudanese populations, where the pronounced genetic heterogeneity...
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