Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

iNOS polymorphism modulates iNOS/NO expression via impaired antioxidant and ROS content in P. vivax and P. falciparum infection.

Redox biology - 1 May 2018

Kumar Amod, Singh Krishn Pratap, Bali Prerna, Anwar Shadab, Kaul Asha, Singh Om P, Gupta Birendra Kumar, Kumari Nutan, Noor Alam Md, Raziuddin Mohammad, Sinha Manoranjan Prasad, Gourinath Samudrala, Sharma Ajay Kumar, Sohail Mohammad

Abstract excerpt

Nitric oxide (NO) has dicotomic influence on modulating host-parasite interplay, synchronizing physiological orchestrations and diagnostic potential; instigated us to investigate the plausible association and genetic regulation among NO level, components of oxidative stress, iNOS polymorphisms and risk of malaria. Here, we experimentally elucidate that iNOS promoter polymorphisms are associated with risk of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Host-Parasite Interactions
Share to Malaria, Falciparum

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Malaria, Vivax

Share to Nitric Oxide

Share to Nitric Oxide Synthase Type II

Share to Plasmodium falciparum

Share to Plasmodium vivax

Share to Reactive Oxygen Species

Source

Open in PubMed Open full text

Identifiers

PMID: 29268202
DOI: 10.1016/j.redox.2017.12.005
PMCID: PMC5738204

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

iNOS polymorphism modulates iNOS/NO expression via impaired antioxidant and ROS content in P. vivax and P. falciparum infection.PMID 29268202Read ↗

NOS2 variants reveal a dual genetic control of nitric oxide levels, susceptibility to Plasmodium infection, and cerebral malaria.Semantic proximity Read ↗

A new NOS2 promoter polymorphism associated with increased nitric oxide production and protection from severe malaria in Tanzanian and Kenyan childrenSemantic proximity Read ↗

Inducible nitric oxide synthase (iNOS) gene polymorphism and disease prevalence.Semantic proximity Read ↗

Nitric oxide synthase 2(Lambaréné) (G-954C), increased nitric oxide production, and protection against malaria.Semantic proximity Read ↗

Question. Do NOS2 promoter polymorphisms protect against malaria?Semantic proximity Read ↗

Involvement of nitric oxide and its up/down stream molecules in the immunity against parasitic infectionsSemantic proximity Read ↗

Genetic variation in neuronal nitric oxide synthase (nNOS) gene and susceptibility to cerebral malaria in Indian adults.Semantic proximity Read ↗

Malaria severity and human nitric oxide synthase type 2 (NOS2) promoter haplotypes.Semantic proximity Read ↗

iNOS promoter variants and severe malaria in Ghanaian children.Semantic proximity Read ↗

A novel polymorphism in nitric oxide synthase interacting protein (NOSIP) modulates nitric oxide and mortality in Human SepsisSemantic proximity Read ↗

Inducible nitric oxide synthase (NOS2) promoter CCTTT repeat polymorphism: relationship to in vivo nitric oxide production/NOS activity in an asymptomatic malaria-endemic population.Semantic proximity Read ↗

Influence of trem-1 gene polymorphisms on cytokine levels during malaria by Plasmodium vivax in a frontier area of the Brazilian Amazon.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.