Article
Performance of genotypic tools for prediction of tropism in HIV-1 subtype C V3 loop sequences.
Intervirology - 1 Jan 2015
Gupta Soham, Neogi Ujjwal, Srinivasa Hiresave, Shet Anita
Abstract excerpt
Currently, there is no consensus on the genotypic tools to be used for tropism analysis in HIV-1 subtype C strains. Thus, the aim of the study was to evaluate the performance of the different V3 loop-based genotypic algorithms available. We compiled a dataset of 645 HIV-1 subtype C V3 loop sequences of known coreceptor phenotypes (531 R5-tropic/non-syncytium-inducing and 114...
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