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Article

Response to Transdermal Selegiline Smoking Cessation Therapy and Markers in the 15q24 Chromosomal Region.

Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco - 1 Sept 2015

Sarginson Jane E, Killen Joel D, Lazzeroni Laura C, Fortmann Stephen P, Ryan Heather S, Ameli Niloufar, Schatzberg Alan F, Murphy Greer M

Abstract excerpt

INTRODUCTION: Current treatments for smoking cessation have limited efficacy. A potential pharmaceutical treatment for smoking cessation is selegiline, a selective and irreversible monoamine oxidase B inhibitor. A few clinical trials have been carried out using selegiline but the results have been mixed. We sought to determine if genetic markers in cholinergic loci in the 15q24 chromosomal region predict response...

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Share to Chromosomes, Human, Pair 15

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Receptors, Nicotinic

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Source

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Identifiers

PMID: 25572450
DOI: 10.1093/ntr/ntu273
PMCID: PMC4627483

Genes

CHRNA5
CHRNB4
CHRNA3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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