Article
Nicotinic acetylcholine receptor variation and response to smoking cessation therapies.
Pharmacogenetics and genomics - 1 Feb 2013
Bergen Andrew W, Javitz Harold S, Krasnow Ruth, Nishita Denise, Michel Martha, Conti David V, Liu Jinghua, Lee Won, Edlund Christopher K, Hall Sharon, Kwok Pui-Yan, Benowitz Neal L, Baker Timothy B, Tyndale Rachel F, Lerman Caryn, Swan Gary E
Abstract excerpt
OBJECTIVE: To evaluate the association of nicotinic acetylcholine receptor (nAChR) single nucleotide polymorphism (SNP) with 7-day point prevalence abstinence (abstinence) in randomized clinical trials of smoking cessation therapies in individuals grouped by pharmacotherapy randomization to inform the development of personalized smoking cessation therapy. MATERIALS AND METHODS: We quantified association of four...
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