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Article

Molecular architecture, structure-function relationship, and importance of the Elp3 subunit for the RNA binding of holo-elongator.

The Journal of biological chemistry - 30 Jul 2004

Petrakis Thodoris G, Wittschieben Birgitte Ø, Svejstrup Jesper Q

Abstract excerpt

The molecular architecture of six-subunit yeast holo-Elongator complex was investigated by the use of immunoprecipitation, two-hybrid interaction mapping, and in vitro studies of binary interactions between individual subunits. Surprisingly, Elp2 is dispensable for the integrity of the holo-Elongator complex, and a purified five-subunit elp2 Delta Elongator complex retains histone acetyltransferase activity in...

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Identifiers

PMID: 15138274
DOI: 10.1074/jbc.M403361200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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