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Article

Animal model of Sar1b deficiency presents lipid absorption deficits similar to Anderson disease.

Journal of molecular medicine (Berlin, Germany) - 1 Feb 2015

Levic Daniel S, Minkel J R, Wang Wen-Der, Rybski Witold M, Melville David B, Knapik Ela W

Abstract excerpt

Anderson disease (ANDD) or chylomicron retention disease (CMRD) is a rare, hereditary lipid malabsorption syndrome associated with mutations in the SAR1B gene that is characterized by failure to thrive and hypocholesterolemia. Although the SAR1B structure has been resolved and its role in formation of coat protein II (COPII)-coated carriers is well established, little is known about the requirement for SAR1B...

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Identifiers

PMID: 25559265
DOI: 10.1007/s00109-014-1247-x
PMCID: PMC4319984

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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