Article

Novel zebrafish mutants reveal new roles for Apolipoprotein B during embryonic development and pathological conditions

2021-04-02

Abstract excerpt

<h4>ABSTRACT</h4> Apolipoprotein B (ApoB) is the primary protein of chylomicrons, VLDLs and LDLs and is essential for their assembly. Defects in ApoB synthesis and secretion result in several human diseases, including abetalipoproteinemia and familial hypobetalipoproteinemia. Conversely, high levels of APOB in plasma are associated with increased risk for coronary heart disease and atherosclerosis. The involvemen...

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Literature Corpus work: 573dc269-89ba-5a81-81d5-fbdbf1e94850
DOI: 10.1101/2021.04.01.437990

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