Article
Homologous recombination repair gene mutations in Malaysian prostate cancer patients.
Cellular and molecular biology (Noisy-le-Grand, France) - 31 Aug 2022
Saeidi Hamidreza, Raju Chandramathi Samudi, Ismail Patimah, Raub Sayyidi Hamzi Abdul, Omar Noorjehan, Hisyam Bakrin Ikmal
Abstract excerpt
Genetic alterations in the homologous recombination repair (HRR) genes are associated with an increased risk of prostate cancer development, and patients harboring these mutations can benefit from targeted therapy. The main aim of this study is to identify genetic alterations in HRR genes as a potential target for targeted treatment. In this study, targeted next generation sequencing (NGS) is used to analyze...
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