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Article

Genetic variation in DNA repair genes and prostate cancer risk: results from a population-based study.

Cancer causes & control : CCC - 1 Feb 2010

Agalliu Ilir, Kwon Erika M, Salinas Claudia A, Koopmeiners Joseph S, Ostrander Elaine A, Stanford Janet L

Abstract excerpt

OBJECTIVE: DNA repair pathways are crucial to prevent accumulation of DNA damage and maintain genomic stability. Alterations of this pathway have been reported in many cancers. An increase in oxidative DNA damage or decrease in DNA repair capacity with aging or due to germline genetic variation may affect prostate cancer risk. METHODS: Pooled data from two population-based studies (1,457 cases and 1,351 controls)...

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Source

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Identifiers

PMID: 19902366
DOI: 10.1007/s10552-009-9461-5
PMCID: PMC2811225

Genes

BRCA2
ERCC2
APEX1
ERCC4
MGMT
MUTYH
OGG1
XPC
XRCC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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