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Article

Impact of DNA repair gene polymorphisms on the risk of biochemical recurrence after radiotherapy and overall survival in prostate cancer.

Oncotarget - 4 Apr 2017

Zanusso Chiara, Bortolus Roberto, Dreussi Eva, Polesel Jerry, Montico Marcella, Cecchin Erika, Gagno Sara, Rizzolio Flavio, Arcicasa Mauro, Novara Giacomo, Toffoli Giuseppe

Abstract excerpt

The identification of biomarkers of biochemical recurrence (BCR) in prostate cancer (PCa) patients undergoing radiotherapy (RT) represents an unanswered clinical issue. The primary aim of this study was the definition of new genetic prognostic biomarkers in DNA repair genes (DRGs), considering both BCR and overall survival (OS) as clinical end-points. The secondary aim was to explore the potential clinical impact...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Open in PubMed Open full text

Identifiers

PMID: 28206966
DOI: 10.18632/oncotarget.15282
PMCID: PMC5410269

Genes

BCR
ERCC2
EXO1
MSH6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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