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Article

Association of reduced folate carrier gene polymorphism and maternal folic acid use with neural tube defects.

American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 5 Sept 2009

Pei Lijun, Liu Jianmeng, Zhang Yewu, Zhu Huiping, Ren Aiguo

Abstract excerpt

This study was designed to investigate whether the risk for neural tube defects (NTDs) was associated with reduced folate carrier gene (RFC1 A80G) polymorphism and/or with the interaction between the RFC1 gene and maternal periconceptional use of folic acid. One hundred four nuclear families with NTDs and 100 non-malformed control families were sampled to investigate the potential interaction between maternal or...

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Source

Identifiers

PMID: 19105199
DOI: 10.1002/ajmg.b.30911

Genes

RFC1

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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