Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Stochastic fluctuations and distributed control of gene expression impact cellular memory.

PloS one - 1 Jan 2014

Corre Guillaume, Stockholm Daniel, Arnaud Ophélie, Kaneko Gaël, Viñuelas José, Yamagata Yoshiaki, Neildez-Nguyen Thi My Anh, Kupiec Jean-Jacques, Beslon Guillaume, Gandrillon Olivier, Paldi András

Abstract excerpt

Despite the stochastic noise that characterizes all cellular processes the cells are able to maintain and transmit to their daughter cells the stable level of gene expression. In order to better understand this phenomenon, we investigated the temporal dynamics of gene expression variation using a double reporter gene model. We compared cell clones with transgenes coding for highly stable mRNA and fluorescent...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Lineage
Share to Computer Simulation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Embryo, Mammalian

Share to Epigenomics

Share to Genes, Reporter

Share to Retinoblastoma

Share to Stochastic Processes

Share to Tumor Cells, Cultured

Source

Open in PubMed Open full text

Identifiers

PMID: 25531401
DOI: 10.1371/journal.pone.0115574
PMCID: PMC4274012

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Stochastic fluctuations and distributed control of gene expression impact cellular memory.PMID 25531401Read ↗

Epigenetic gene expression noise and phenotypic diversification of clonal cell populations.Semantic proximity Read ↗

Epigenetic fluctuations underlie gene expression timescales and variability.Semantic proximity Read ↗

Epigenetic modulations rendering cell-to-cell variability and phenotypic metastability.Semantic proximity Read ↗

Gene expression variations are predictive for stochastic noise.Semantic proximity Read ↗

Stochasticity in gene expression: from theories to phenotypes.Semantic proximity Read ↗

Two DNA-encoded strategies for increasing expression with opposing effects on promoter dynamics and transcriptional noise.Semantic proximity Read ↗

Functional roles of microbial cell-to-cell heterogeneity and emerging technologies for analysis and control.Semantic proximity Read ↗

Characterization of stem cells and cancer cells on the basis of gene expression profile stability, plasticity, and robustness: dynamical systems theory of gene expressions under cell-cell interaction explains mutational robustness of differentiated cells and suggests how cancer cells emerge.Semantic proximity Read ↗

Enhancement of cellular memory by reducing stochastic transitions.Semantic proximity Read ↗

Distinct allelic patterns of nanog expression impart embryonic stem cell population heterogeneity.Semantic proximity Read ↗

Clonally heritable gene expression imparts a layer of diversity within cell typesSemantic proximity Read ↗

Analytical distributions for detailed models of stochastic gene expression in eukaryotic cells.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.