Article
Gene expression variations are predictive for stochastic noise.
Nucleic acids research - 1 Jan 2011
Dong Dong, Shao Xiaojian, Deng Naiyang, Zhang Zhaolei
Abstract excerpt
Fluctuations in protein abundance among single cells are primarily due to the inherent stochasticity in transcription and translation processes, such stochasticity can often confer phenotypic heterogeneity among isogenic cells. It has been proposed that expression noise can be triggered as an adaptation to environmental stresses and genetic perturbations, and as a mechanism to facilitate gene expression...
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