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Article

High IDH1 expression is associated with a poor prognosis in cytogenetically normal acute myeloid leukemia.

International journal of cancer - 1 Sept 2015

Ma Qiu-Ling, Wang Jing-Han, Wang Yun-Gui, Hu Chao, Mu Qi-Tian, Yu Meng-Xia, Wang Lei, Wang Dong-Mei, Yang Min, Yin Xiu-Feng, Chen Fei-Fei, Lu Sha-Sha, Chen Jian, Zhu Zhi-Juan, Chen Sai-Juan, Jin Jie

Abstract excerpt

The prognostic value of IDH1 mutations has been systematically evaluated in acute myeloid leukemia (AML) patients recently. However, the role of IDH1 expression in AML is still under exploration. To investigate the clinical significance, we analyzed the IDH1/2 expression in 320 patients with cytogenetically normal AML (CN-AML) by quantitative real-time reverse-transcription polymerase chain reaction. High...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 25523507
DOI: 10.1002/ijc.29395

Genes

IDH1
FLT3
IDH2
NPM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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