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Article

Acquired mutations in the genes encoding IDH1 and IDH2 both are recurrent aberrations in acute myeloid leukemia: prevalence and prognostic value.

Blood - 23 Sept 2010

Abbas Saman, Lugthart Sanne, Kavelaars François G, Schelen Anita, Koenders Jasper E, Zeilemaker Annelieke, van Putten Wim J L, Rijneveld Anita W, Löwenberg Bob, Valk Peter J M

Abstract excerpt

Somatic mutations in isocitrate dehydrogenase 1 and 2 (IDH1 and IDH2) were recently demonstrated in acute myeloid leukemia (AML), but their prevalence and prognostic impact remain to be explored in large extensively characterized AML series, and also in various other hematologic malignancies. Her...

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Source

Identifiers

PMID: 20538800
DOI: 10.1182/blood-2009-11-250878

Genes

IDH1
IDH2
NPM1
FLT3
JAK2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20538800-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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Acquired mutations in the genes encoding IDH1 and IDH2 both are recurrent aberrations in acute myeloid leukemia: prevalence and prognostic value.PMID 20538800Read ↗

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