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Article

Prognostic value of PLCE1 expression in upper gastrointestinal cancer: a systematic review and meta-analysis.

Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2014

Cui Xiao-Bin, Peng Hao, Li Su, Li Ting-Ting, Liu Chun-Xia, Zhang Shu-Mao, Jin Ting-Ting, Hu Jian-Ming, Jiang Jin-Fang, Liang Wei-Hua, Li Na, Li Li, Chen Yun-Zhao, Li Feng

Abstract excerpt

BACKGROUND: A number of studies have identified a shared susceptibility locus in phospholipase C epsilon 1 (PLCE1) for esophageal squamous cell carcinoma (ESCC) and gastric cardia adenocarcinomas (GCA). However, the results of PLCE1 expression in esophageal and gastric cancer remain inconsistent and controversial. Moreover, the effects on clinicopathological features remain undetermined. This study aimed to...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 25520085
DOI: 10.7314/apjcp.2014.15.22.9661

Genes

PLCE1
GCA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

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Research trail→

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Prognostic value of PLCE1 expression in upper gastrointestinal cancer: a systematic review and meta-analysis.PMID 25520085Read ↗

PLCE1 rs2274223 A>G polymorphism and cancer risk: a meta-analysis.Semantic proximity Read ↗

Putatively functional PLCE1 variants and susceptibility to esophageal squamous cell carcinoma (ESCC): a case-control study in eastern Chinese populations.Semantic proximity Read ↗

Two novel polymorphisms in PLCE1 are associated with the susceptibility to esophageal squamous cell carcinoma in Chinese population.Semantic proximity Read ↗

Novel functional variants locus in PLCE1 and susceptibility to digestive tract cancer in the Chinese population: a meta-analysis.Semantic proximity Read ↗

Meta-analysis of phospholipase C epsilon 1 polymorphism and cancer risk.Semantic proximity Read ↗

Genetic variants in GHR and PLCE1 genes are associated with susceptibility to esophageal cancer.Semantic proximity Read ↗

Esophageal squamous cell carcinoma and gastric cardia adenocarcinoma shared susceptibility locus in PLCE1: a meta-analysis.Semantic proximity Read ↗

PLC-ε1 gene polymorphisms significantly enhance the risk of esophageal squamous cell carcinoma in individuals with a family history of upper gastrointestinal cancers.Semantic proximity Read ↗

Novel functional variants locus in PLCE1 and susceptibility to esophageal squamous cell carcinoma: based on published genome-wide association studies in a central Chinese population.Semantic proximity Read ↗

PLCE1 mRNA and protein expression and survival of patients with esophageal squamous cell carcinoma and gastric adenocarcinoma.Semantic proximity Read ↗

Replication study of PLCE1 and C20orf54 polymorphism and risk of esophageal cancer in a Chinese population.Semantic proximity Read ↗

Phospholipase C epsilon 1 (PLCE1 rs2274223A>G, rs3765524C>T and rs7922612C>T) polymorphisms and esophageal cancer risk in the Kashmir Valley.Semantic proximity Read ↗

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