Genetic variants in GHR and PLCE1 genes are associated with susceptibility to esophageal cancer.

doi:10.1002/mgg3.1474

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Article

Genetic variants in GHR and PLCE1 genes are associated with susceptibility to esophageal cancer.

Molecular genetics & genomic medicine - 1 Oct 2020

Wang Rong, Si Lining, Zhu Derui, Shen Guoping, Long Qifu, Zhao Yanli

Abstract excerpt

BACKGROUND: Esophageal cancer (EC) is the leading cause of cancer-related mortality worldwide. The underlying genetic risk factors remain unclear. The association between gene growth hormone receptor (GHR) and phospholipase C epsilon 1 (PLCE1) polymorphisms and the EC risk were identified in this study. METHODS: A total of 506 EC cases and 507 controls were included in this research. Two SNPs (rs6898743 of GHR...

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Identifiers

PMID: 32869542
DOI: 10.1002/mgg3.1474
PMCID: PMC7549587

Genes

GHR
PLCE1
GC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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