PLCE1 rs2274223 A>G polymorphism and cancer risk: a meta-analysis.

doi:10.1007/s13277-013-0932-7

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Article

PLCE1 rs2274223 A>G polymorphism and cancer risk: a meta-analysis.

Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Dec 2013

Umar Meenakshi, Upadhyay Rohit, Mittal Balraj

Abstract excerpt

Phospholipase C epsilon 1 gene (PLCE1) encodes a phospholipase enzyme which regulates various physiological processes (cell growth, differentiation, and apoptosis) and is supposed to play a critical role in carcinogenesis. Recently, a single nucleotide polymorphism (rs2274223 A>G) in PLCE1 was reported as a novel susceptibility locus for esophageal and gastric cancers by genome-wide association studies performed...

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Identifiers

PMID: 23797815
DOI: 10.1007/s13277-013-0932-7

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PLCE1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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