Article
PLCE1 mRNA and protein expression and survival of patients with esophageal squamous cell carcinoma and gastric adenocarcinoma.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Aug 2014
Li Wen-Qing, Hu Nan, Burton Victoria H, Yang Howard H, Su Hua, Conway Catherine M, Wang Lemin, Wang Chaoyu, Ding Ti, Xu Yi, Giffen Carol, Abnet Christian C, Goldstein Alisa M, Hewitt Stephen M, Taylor Philip R
Abstract excerpt
BACKGROUND: Germline genetic variants in PLCE1 (10q23) have demonstrated consistent associations with risk of esophageal squamous cell carcinoma (ESCC) and gastric cancer among Chinese. We evaluated PLCE1 mRNA and protein expression in paired tumor-normal tissues, and their relationship with survival. METHODS: PLCE1 mRNA was profiled using three probes in the Affymetrix GeneChip U133 for paired tumor-normal...
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