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Article

Establishing high resolution melting analysis: method validation and evaluation for c-RET proto-oncogene mutation screening.

Clinical chemistry and laboratory medicine - 6 Oct 2011

Benej Martin, Bendlova Bela, Vaclavikova Eliska, Poturnajova Martina

Abstract excerpt

BACKGROUND: Reliable and effective primary screening of mutation carriers is the key condition for common diagnostic use. The objective of this study is to validate the method high resolution melting (HRM) analysis for routine primary mutation screening and accomplish its optimization, evaluation and validation. Due to their heterozygous nature, germline point mutations of c-RET proto-oncogene, associated to...

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Source

Identifiers

PMID: 21973105
DOI: 10.1515/CCLM.2011.730

Genes

RET

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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