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Article

Baseline interpatient hepatitis B viral diversity differentiates HBsAg outcomes in patients treated with tenofovir disoproxil fumarate.

Journal of hepatology - 1 May 2015

Charuworn Prista, Hengen Paul N, Aguilar Schall Raul, Dinh Phillip, Ge Dongliang, Corsa Amoreena, Reesink Hendrik W, Zoulim Fabien, Kitrinos Kathryn M

Abstract excerpt

BACKGROUND AND AIMS: HBsAg loss is a desired, but rare, treatment-induced clinical endpoint in chronic hepatitis B (CHB). Few studies have evaluated viral factors contributing to HBsAg loss. METHODS: This study evaluated baseline interpatient sequence diversity across the HBV genome in tenofovir disoproxil fumarate-treated patients who lost HBsAg and compared it to that of control patients with high HBsAg levels...

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Share to Antiviral Agents
Share to Disease Transmission, Infectious

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA, Viral

Share to Hepatitis B, Chronic

Share to Hepatitis B e Antigens

Share to Hepatitis B Surface Antigens

Share to Hepatitis B virus

Share to Tenofovir

Source

Identifiers

PMID: 25514556
DOI: 10.1016/j.jhep.2014.12.008

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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