Article
Effects of long-term tenofovir-based combination antiretroviral therapy in HIV-hepatitis B virus coinfection on persistent hepatitis B virus viremia and the role of hepatitis B virus quasispecies diversity.
AIDS (London, England) - 19 Jun 2016
Audsley Jennifer, Bent Stephen J, Littlejohn Margaret, Avihingsanon Anchalee, Matthews Gail, Bowden Scott, Bayliss Julianne, Luciani Fabio, Yuen Lilly, Fairley Christopher K, Locarnini Stephen, Lewin Sharon R, Sasadeusz Joe
Abstract excerpt
OBJECTIVE: Hepatitis B virus (HBV) can persist in some HIV-HBV coinfected individuals on tenofovir disoproxil fumarate (TDF)-containing combination antiretroviral therapy (cART) but HBV resistance to TDF has not been reported and the source of persistent HBV DNA on TDF is poorly understood. The aims of this study were to assess long-term HBV suppression in HIV-HBV coinfected individuals receiving TDF and...
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