Article
Plasmodium falciparum field isolates from areas of repeated emergence of drug resistant malaria show no evidence of hypermutator phenotype.
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Mar 2015
Brown Tyler S, Jacob Christopher G, Silva Joana C, Takala-Harrison Shannon, Djimdé Abdoulaye, Dondorp Arjen M, Fukuda Mark, Noedl Harald, Nyunt Myaing Myaing, Kyaw Myat Phone, Mayxay Mayfong, Hien Tran Tinh, Plowe Christopher V, Cummings Michael P
Abstract excerpt
Multiple transcontinental waves of drug resistance in Plasmodium falciparum have originated in Southeast Asia before spreading westward, first into the rest of Asia and then to sub-Saharan Africa. In vitro studies have suggested that hypermutator P. falciparum parasites may exist in Southeast Asi...
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