Article
Evidence of a Mild Mutator Phenotype in Cambodian Plasmodium falciparum Malaria Parasites.
PloS one - 1 Jan 2016
Lee Andrew H, Fidock David A
Abstract excerpt
Malaria control efforts have been continuously stymied by drug-resistant strains of Plasmodium falciparum, which typically originate in Southeast Asia prior to spreading into high-transmission settings in Africa. One earlier proposed explanation for Southeast Asia being a hotbed of resistance has been the hypermutability or "Accelerated Resistance to Multiple Drugs" (ARMD) phenotype, whereby multidrug-resistant...
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