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Genomic structure and diversity of Plasmodium falciparum in Southeast Asia reveal recent parasite migration patterns

17 Jun 2019

Abstract excerpt

Estimates of Plasmodium falciparum migration may inform strategies for malaria elimination. Here we elucidate fine-scale parasite population structure and infer recent migration across Southeast Asia using identity-by-descent (IBD) approaches based on genome-wide single nucleotide polymorphisms called in 1722 samples from 54 districts. IBD estimates are consistent with isolation-by-distance. We observe greater...

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PMID: 31209259
DOI: 10.1038/s41467-019-10121-3

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