Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Population Parameters Underlying an Ongoing Soft Sweep in Southeast Asian Malaria Parasites.

Molecular biology and evolution - 1 Jan 2017

Anderson Timothy J C, Nair Shalini, McDew-White Marina, Cheeseman Ian H, Nkhoma Standwell, Bilgic Fatma, McGready Rose, Ashley Elizabeth, Pyae Phyo Aung, White Nicholas J, Nosten François

Abstract excerpt

Multiple kelch13 alleles conferring artemisinin resistance (ART-R) are currently spreading through Southeast Asian malaria parasite populations, providing a unique opportunity to observe an ongoing soft selective sweep, investigate why resistance alleles have evolved multiple times and determine fundamental population genetic parameters for Plasmodium We sequenced kelch13 (n = 1,876), genotyped 75 flanking SNPs,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antimalarials
Share to Artemisinins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Drug Resistance

Share to Malaria, Falciparum

Share to Mutation Rate

Share to Plasmodium falciparum

Share to Protozoan Proteins

Share to Thailand

Source

Open in PubMed Open full text

Identifiers

PMID: 28025270
DOI: 10.1093/molbev/msw228
PMCID: PMC5216669

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Population Parameters Underlying an Ongoing Soft Sweep in Southeast Asian Malaria Parasites.PMID 28025270Read ↗

Fitness Costs and the Rapid Spread of kelch13-C580Y Substitutions Conferring Artemisinin Resistance.Semantic proximity Read ↗

Emergence and Spread of kelch13 Mutations Associated with Artemisinin Resistance in Plasmodium falciparum Parasites in 12 Thai Provinces from 2007 to 2016.Semantic proximity Read ↗

Independent emergence of artemisinin resistance mutations among Plasmodium falciparum in Southeast Asia.Semantic proximity Read ↗

Pooled sequencing and rare variant association tests for identifying the determinants of emerging drug resistance in malaria parasites.Semantic proximity Read ↗

A major genome region underlying artemisinin resistance in malaria.Semantic proximity Read ↗

Natural selection of K13 mutants of Plasmodium falciparum in response to artemisinin combination therapies in Thailand.Semantic proximity Read ↗

Selection and spread of artemisinin-resistant alleles in Thailand prior to the global artemisinin resistance containment campaign.Semantic proximity Read ↗

Understanding the Global Spread of Artemisinin Resistance: Insights from over 100K <i>Plasmodium falciparum</i> SamplesSemantic proximity Read ↗

A Worldwide Map of Plasmodium falciparum K13-Propeller Polymorphisms.Semantic proximity Read ↗

Kelch 13-propeller polymorphisms in Plasmodium falciparum from Jazan region, southwest Saudi Arabia.Semantic proximity Read ↗

Polymorphisms in the K13 Gene in Plasmodium falciparum from Different Malaria Transmission Areas of Kenya.Semantic proximity Read ↗

Plasmodium falciparum Kelch 13 mutations and treatment response in patients in Hpa-Pun District, Northern Kayin State, Myanmar.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.