Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

In-vivo longitudinal MRI study: an assessment of melanoma brain metastases in a clinically relevant mouse model.

Melanoma research - 1 Apr 2015

Henry Mariama N, Chen Yuhua, McFadden Catherine D, Simedrea Felicia C, Foster Paula J

Abstract excerpt

Brain metastases are an important clinical problem. Few animal models exist for melanoma brain metastases; many of which are not clinically relevant. Longitudinal MRI was implemented to examine the development of tumors in a clinically relevant mouse model of melanoma brain metastases. Fifty thousand human metastatic melanoma (A2058) cells were injected intracardially into nude mice. Three Tesla MRI was performed...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Brain Neoplasms
Share to Contrast Media

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Equipment Design

Share to Magnetic Resonance Imaging

Share to Melanoma

Share to Mice, Nude

Share to Skin Neoplasms

Share to Tumor Burden

Source

Identifiers

PMID: 25513779
DOI: 10.1097/CMR.0000000000000136

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

In-vivo longitudinal MRI study: an assessment of melanoma brain metastases in a clinically relevant mouse model.PMID 25513779Read ↗

Unraveling the Enigma of Melanoma Brain Metastasis: New Horizons in Mechanisms, Diagnosis, and TherapySemantic proximity Read ↗

Melanoma-secreted Amyloid Beta Suppresses Neuroinflammation and Promotes Brain MetastasisSemantic proximity Read ↗

Transcriptome analysis of novel B16 melanoma metastatic variants generated by serial intracarotid artery injectionSemantic proximity Read ↗

Does the distribution pattern of brain metastases during BRAF inhibitor therapy reflect phenotype switching?Semantic proximity Read ↗

Route-dependent Dissemination with Conserved Blood–Tumor Barrier Ultrastructure in Intracranial Metastasis ModelsSemantic proximity Read ↗

Melanoma brain colonization involves the emergence of a brain-adaptive phenotypeSemantic proximity Read ↗

The metastatic microenvironment: Brain-derived soluble factors alter the malignant phenotype of cutaneous and brain-metastasizing melanoma cells.Semantic proximity Read ↗

The metastatic microenvironment: Claudin-1 suppresses the malignant phenotype of melanoma brain metastasis.Semantic proximity Read ↗

Belvarafenib penetrates the BBB and shows potent antitumor activity in a murine melanoma brain metastasis model.Semantic proximity Read ↗

Melanoma brain metastases and vemurafenib: need for further investigation.Semantic proximity Read ↗

Antiangiogenic therapy of cerebral melanoma metastases results in sustained tumor progression via vessel co-option.Semantic proximity Read ↗

Brain metastasis model in athymic nude mice using a novel MUC1-secreting human breast-cancer cell line, MA11Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.