Article
The role of apolipoprotein E genetic variants in lipoprotein disorders.
Journal of internal medicine - 1 Jun 1992
Rall S C, Mahley R W
Abstract excerpt
Apolipoprotein E plays a central role in lipoprotein metabolism by serving as a ligand for the binding of lipoproteins to lipoprotein receptors. Both common and rare variants of apoE have been described. The common variants apoE2 and apoE4 have a significant impact on interindividual variation of lipid and lipoprotein levels in normal subjects. The common variant apoE2 and more than half a dozen rare variants are...
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