Article
The role of apolipoprotein E genetic variants in lipoprotein disorders.
Journal of internal medicine - 1 Jun 1992
Rall S C, Mahley R W
Abstract excerpt
Apolipoprotein E plays a central role in lipoprotein metabolism by serving as a ligand for the binding of lipoproteins to lipoprotein receptors. Both common and rare variants of apoE have been described. The common variants apoE2 and apoE4 have a significant impact on interindividual variation of...
Topics
- Apolipoproteins E
- Genes, Dominant
- Genes, Recessive
- Genetic Variation
- Humans
- Hyperlipidemias
- Hyperlipoproteinemia Type III
- Mutation
- Polymorphism, Genetic