Article
Association between HBV Pre-S mutations and the intracellular HBV DNAs in HBsAg-positive hepatocellular carcinoma in China.
Clinical and experimental medicine - 1 Nov 2015
Wang Hui, Wang Ai-Hua, Gressner Olav A, Fang Meng, Gu Xing, Ji Qiang, Cheng Shu-Qun, Shen Feng, Gao Chun-Fang
Abstract excerpt
This study aimed to investigate the association between HBV mutations and intrahepatic HBV status and to determine the clinical features and the contribution of HBV mutations to postoperative prognosis for hepatocellular carcinoma (HCC) patients with HBsAg (+) in China. Using TaqMan fluorescent real-time PCR, HBV covalently closed circular DNA (cccDNA) and total DNA (tDNA) were both quantified in 106 pairs of...
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