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Comparative mechanisms of cancer cell migration through 3D matrix and physiological microtracks

11 Dec 2014

Abstract excerpt

Tumor cell invasion through the stromal extracellular matrix (ECM) is a key feature of cancer metastasis, and understanding the cellular mechanisms of invasive migration is critical to the development of effective diagnostic and therapeutic strategies. Since cancer cell migration is highly adaptable to physiochemical properties of the ECM, it is critical to define these migration mechanisms in a context-specific...

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PMID: 25500742
DOI: 10.1152/ajpcell.00225.2014

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