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Article

A flexible reporter system for direct observation and isolation of cancer stem cells.

Stem cell reports - 13 Jan 2015

Tang Binwu, Raviv Asaf, Esposito Dominic, Flanders Kathleen C, Daniel Catherine, Nghiem Bao Tram, Garfield Susan, Lim Langston, Mannan Poonam, Robles Ana I, Smith William I, Zimmerberg Joshua, Ravin Rea, Wakefield Lalage M

Abstract excerpt

Many tumors are hierarchically organized with a minority cell population that has stem-like properties and enhanced ability to initiate tumorigenesis and drive therapeutic relapse. These cancer stem cells (CSCs) are typically identified by complex combinations of cell-surface markers that differ among tumor types. Here, we developed a flexible lentiviral-based reporter system that allows direct visualization of...

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PMID: 25497455
DOI: 10.1016/j.stemcr.2014.11.002
PMCID: PMC4297872

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SOX2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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