Article
Rapid phenotyping of cancer stem cells using multichannel nanosensor arrays.
Nanomedicine : nanotechnology, biology, and medicine - 1 Aug 2018
Geng Yingying, Goel Hira L, Le Ngoc B, Yoshii Tatsuyuki, Mout Rubul, Tonga Gulen Y, Amante John J, Mercurio Arthur M, Rotello Vincent M
Abstract excerpt
Cancer stem cells (CSCs) contribute to multidrug resistance, tumor recurrence and metastasis, making them prime therapeutic targets. Their ability to differentiate and lose stem cell properties makes them challenging to study. Currently, there is no simple assay that can quickly capture and trace the dynamic phenotypic changes on the CSC surface. Here, we report rapid discrimination of breast CSCs from non-CSCs...
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