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Reporters of Cancer Stem Cells as a Tool for Drug Discovery

22 Apr 2021

Abstract excerpt

In view of the importance of cancer stem cells (CSCs) in chemoresistance, metastasis and recurrence, the biology of CSCs were explored in detail. Based on that, several modalities were proposed to target them. In spite of the several clinical trials, a successful CSC-targeting drug is yet to be identified. The number of molecules screened and entered for clinical trial for CSC-targeting is comparatively low,...

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PMID: 33968778
DOI: 10.3389/fonc.2021.669250

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