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Article

Pharmacogenomics of antimicrobial agents.

Pharmacogenomics - 1 Jan 2014

Aung Ar Kar, Haas David W, Hulgan Todd, Phillips Elizabeth J

Abstract excerpt

Antimicrobial efficacy and toxicity varies between individuals owing to multiple factors. Genetic variants that affect drug-metabolizing enzymes may influence antimicrobial pharmacokinetics and pharmacodynamics, thereby determining efficacy and/or toxicity. In addition, many severe immune-mediated reactions have been associated with HLA class I and class II genes. In the last two decades, understanding of...

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Identifiers

PMID: 25495412
DOI: 10.2217/pgs.14.147
PMCID: PMC4296903

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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