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Article

Pharmacogenomics of adverse drug reactions: implementing personalized medicine.

Human molecular genetics - 15 Oct 2012

Wei Chun-Yu, Lee Ming-Ta Michael, Chen Yuan-Tsong

Abstract excerpt

Pharmacogenomics aims to investigate the genetic basis of inter-individual differences in drug responses, such as efficacy, dose requirements and adverse events. Research in pharmacogenomics has grown over the past decade, evolving from a candidate-gene approach to genome-wide association studies (GWASs). Genetic variants in genes coding for drug metabolism, drug transport and more recently human-leukocyte...

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PMID: 22907657
DOI: 10.1093/hmg/dds341

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