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Article

The disruption of prenylation leads to pleiotropic rearrangements in cellular behavior in Staphylococcus aureus.

Molecular microbiology - 1 Mar 2015

Krute Christina N, Carroll Ronan K, Rivera Frances E, Weiss Andy, Young Ryan M, Shilling Andrew, Botlani Mohsen, Varma Sameer, Baker Bill J, Shaw Lindsey N

Abstract excerpt

Prenylation is the addition of prenyl groups to peptide chains or metabolites via the condensation of geranyl- or isopentenyl-diphosphate moieties by geranyltranstransferases. Although this process is extensively studied in eukaryotes, little is known about the influence of prenylation in prokaryotic species. To explore the role of this modification in bacteria, we generated a mutation in the...

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Identifiers

PMID: 25491272
DOI: 10.1111/mmi.12900

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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