Article

Non-canonical stringent response signaling mediates antimicrobial fatty acid sensitivity in <i>Staphylococcus aureus</i>

2026-02-02

Abstract excerpt

Staphylococcus aureus is a leading cause of skin and soft tissue infections, yet colonization of healthy skin is limited by multiple defenses, including antimicrobial fatty acids (AFAs) produced by host cells and the resident microbiota. The mechanisms by which S. aureus overcomes these lipid-based defenses remain incompletely understood. Here, we show that mutations truncating the essential stringent response re...

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Literature Corpus work: 08248a79-3275-5018-8f12-15f4ac8c1d5b
DOI: 10.64898/2026.02.01.703180

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