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Article

Crucial Role for Lipoteichoic Acid Assembly in the Metabolic Versatility and Antibiotic Resistance of Staphylococcus aureus.

Infection and immunity - 18 Jul 2023

Burtchett Troy A, Shook John C, Hesse Laura E, Delekta Philip C, Brzozowski Robert S, Nouri Alhakam, Calas Alexa J, Spanoudis Catherine M, Eswara Prahathees J, Hammer Neal D

Abstract excerpt

Staphylococcus aureus is a public health threat due to the prevalence of antibiotic resistance and the capacity of this organism to infect numerous organs in vertebrates. To generate energy needed to proliferate within tissues, S. aureus transitions between aerobic respiration and fermentation. Fermentation results in a distinct colony morphology called the small-colony variant (SCV) due to decreased membrane...

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Drug Resistance, Microbial
Lipopolysaccharides
Mutation
Staphylococcal Infections
Staphylococcus aureus

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 37347167
DOI: 10.1128/iai.00550-22
PMCID: PMC10353449

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