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Article

Increased osteoclastogenesis in mice lacking the carcinoembryonic antigen-related cell adhesion molecule 1.

PloS one - 1 Jan 2014

Heckt Timo, Bickert Thomas, Jeschke Anke, Seitz Sebastian, Schulze Jochen, Ito Wulf D, Zimmermann Wolfgang, Amling Michael, Schinke Thorsten, Horst Andrea Kristina, Keller Johannes

Abstract excerpt

Alterations in bone remodeling are a major public health issue, as therapeutic options for widespread bone disorders such as osteoporosis and tumor-induced osteolysis are still limited. Therefore, a detailed understanding of the regulatory mechanism governing bone cell differentiation in health and disease are of utmost clinical importance. Here we report a novel function of carcinoembryonic antigen-related cell...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 25490771
DOI: 10.1371/journal.pone.0114360
PMCID: PMC4260834

Genes

CEACAM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

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