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Article

CD8+ T Cells Control Ross River Virus Infection in Musculoskeletal Tissues of Infected Mice

9 Dec 2014

Abstract excerpt

Ross River virus (RRV), chikungunya virus, and related alphaviruses cause debilitating polyarthralgia and myalgia. Mouse models of RRV and chikungunya virus have demonstrated a role for the adaptive immune response in the control of these infections. However, questions remain regarding the role for T cells in viral control, including the magnitude, location, and dynamics of CD8(+) T cell responses. To address...

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PMID: 25488988
DOI: 10.4049/jimmunol.1401833

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