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Sindbis-Group Alphavirus Replication in Periosteum and Endosteum of Long Bones in Adult Mice

1 Oct 2000

Abstract excerpt

Several alphaviruses, including the Sindbis-group viruses, Ross River virus, O'nyong-nyong virus, and Chikungunya virus, are associated with outbreaks of acute and persistent arthralgia and arthritis in humans. Mechanisms underlying alphavirus-induced arthralgia and arthritis are not clearly understood, though direct viral replication within or around the affected joints is thought to contribute to disease....

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PMID: 10982376
DOI: 10.1128/jvi.74.19.9294-9299.2000

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