Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Motor phenotype of LRRK2-associated Parkinson's disease: a Tunisian longitudinal study.

Movement disorders : official journal of the Movement Disorder Society - 1 Feb 2015

Nabli Fatma, Ben Sassi Samia, Amouri Rim, Duda John E, Farrer Matthew J, Hentati Fayçal

Abstract excerpt

Mutations in the leucine-rich repeat kinase 2 gene (LRRK2) were found to be a significant cause of late-onset autosomal dominant forms of Parkinson's disease (PD). To determine the motor characteristics of LRRK2-related disease, we conducted a longitudinal study of 58 G2019S LRRK2-associated PD patients and compared them with genetically undefined (GU) PD patients. Fifty-eight patients diagnosed with PD-related...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Aged, 80 and over

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Leucine-Rich Repeat Serine-Threonine Protein Kinase-2

Share to Longitudinal Studies

Share to Parkinson Disease

Share to Protein Serine-Threonine Kinases

Share to Tunisia

Source

Identifiers

PMID: 25487881
DOI: 10.1002/mds.26097

Genes

PINK1
PRKN
SNCA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Motor phenotype of LRRK2-associated Parkinson's disease: a Tunisian longitudinal study.PMID 25487881Read ↗

Comparative study of Parkinson's disease and leucine-rich repeat kinase 2 p.G2019S parkinsonism.Semantic proximity Read ↗

LRRK2 G2019S Parkinson's disease with more benign phenotype than idiopathic.Semantic proximity Read ↗

LRRK2 Gly2019Ser penetrance in Arab-Berber patients from Tunisia: a case-control genetic study.Semantic proximity Read ↗

Comprehensive analysis of clinical and biological features in Parkinson's disease associated with the LRRK2 G2019S mutation: Data from the PPMI study.Semantic proximity Read ↗

Motor phenotype of LRRK2 G2019S carriers in early-onset Parkinson disease.Semantic proximity Read ↗

<i>LRRK2</i> parkinsonism in Tunisia and Norway: A comparative analysis of disease penetranceSemantic proximity Read ↗

Effect of a Leucine-rich Repeat Kinase 2 Variant on Motor and Non-motor Symptoms in Chinese Parkinson’s Disease PatientsSemantic proximity Read ↗

Motor and nonmotor heterogeneity of LRRK2-related and idiopathic Parkinson's disease.Semantic proximity Read ↗

Cognitive dysfunction in Tunisian LRRK2 associated Parkinson's disease.Semantic proximity Read ↗

Motor and non-motor features of Parkinson's disease in LRRK2 G2019S carriers versus matched controls.Semantic proximity Read ↗

Parkinson disease phenotype in Ashkenazi Jews with and without LRRK2 G2019S mutations.Semantic proximity Read ↗

Clinical features of Parkinson disease patients with homozygous leucine-rich repeat kinase 2 G2019S mutations.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.