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Article

LRRK2 G2019S Parkinson's disease with more benign phenotype than idiopathic.

Acta neurologica Scandinavica - 1 Nov 2018

Ben Romdhan Sawssan, Farhat Nouha, Nasri Amina, Lesage Suzanne, Hdiji Olfa, Ben Djebara Mouna, Landoulsi Zied, Stevanin Giovanni, Brice Alexis, Damak Mariem, Gouider Riadh, Mhiri Chokri

Abstract excerpt

OBJECTIVES: The LRRK2-G2019S mutation is the most common cause of Parkinson's disease (PD) in North Africa. G2019S-PD has been described as similar to idiopathic with minor clinical differences. The aim of this study was to determine the G2019S-related phenotype and to investigate gender and gene dosage effects on clinical features of G2019S carriers. PATIENTS AND METHODS: The G2019S mutation was screened in 250...

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PMID: 29989150
DOI: 10.1111/ane.12996

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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