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Article

Genetic association of single nucleotide polymorphisms in P53 pathway with gastric cancer risk in a Chinese Han population.

Medical oncology (Northwood, London, England) - 1 Jan 2015

Wu Guo-Cong, Zhang Zhong-Tao

Abstract excerpt

The tumor suppressor gene P53 plays an important role in carcinogenesis, and the P53 pathway is central both in reducing cancer frequency and in mediating the response of cancer therapies. MDM2, MDM4 and Hausp genes are all critical regulators of the tumor suppressor P53. Many studies have evaluated the association of single nucleotide polymorphisms (SNPs) in P53 pathway with the risk of common cancers. However,...

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Source

Identifiers

PMID: 25479941
DOI: 10.1007/s12032-014-0401-1

Genes

MDM2
MDM4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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