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A Shared Susceptibility Locus in the p53 Gene for both Gastric and Esophageal Cancers in a Northwestern Chinese Population.

Genetic testing and molecular biomarkers - 1 Dec 2020

Cao Juan, Chen Zhiqiang, Tian Chaoyong, Yu Jia, Zhang Hongfei, Yang Jingwen, Yang Wenjun

Abstract excerpt

Background: Upper gastrointestinal tract cancers are the leading causes of cancer-related deaths in Northwest China and they share many similarities in terms of histological type, risk factors, and genetic variants. We hypothesized that shared common single-nucleotide polymorphisms (SNPs) in the p53 pathway exist between patients with gastric and esophageal cancer (EC) patients. Materials and Methods: A...

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Identifiers

PMID: 33290139
DOI: 10.1089/gtmb.2020.0192

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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