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Article

FcγRIIb inhibits immune complex-induced VEGF-A production and intranodal lymphangiogenesis.

Proceedings of the National Academy of Sciences of the United States of America - 16 Dec 2014

Clatworthy Menna R, Harford Sarah K, Mathews Rebeccah J, Smith Kenneth G C

Abstract excerpt

IgG immune complexes (ICs) are generated during immune responses to infection and self-antigen and have been implicated in the pathogenesis of autoimmune diseases such as systemic lupus erythematosus (SLE). Their role, and that of the fragment crystallizable (Fc) receptors that bind them, in driving local inflammation is not fully understood. Low affinity-activating Fcγ receptors (FcγRs) that bind immune...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 25475856
DOI: 10.1073/pnas.1413915111
PMCID: PMC4273345

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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