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Article

The nicotinic acetylcholine receptor Dalpha7 is required for an escape behavior in Drosophila.

PLoS biology - 1 Mar 2006

Fayyazuddin Amir, Zaheer Mahira A, Hiesinger P Robin, Bellen Hugo J

Abstract excerpt

Acetylcholine is the major excitatory neurotransmitter in the central nervous system of insects. Mutant analysis of the Dalpha7 nicotinic acetylcholine receptor (nAChR) of Drosophila shows that it is required for the giant fiber-mediated escape behavior. The Dalpha7 protein is enriched in the dendrites of the giant fiber, and electrophysiological analysis of the giant fiber circuit showed that sensory input to...

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Identifiers

PMID: 16494528
DOI: 10.1371/journal.pbio.0040063
PMCID: PMC1382016

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Source receipt: pubmed, retrieved 7 Sept 2026.

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